JAMA 292 (14), 17241737 (2004) D.A
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In response to cold exposure, beta-adrenergic stimulation, or exercise, WAT can undergo phenotypic switching (browning) into beige adipose tissues that, though arising from distinct developmental origins from BAT [37], are similar to BAT in morphological features as well as in pro-lipolytic, anti-inflammatory, and UCP1-mediated thermogenic properties [38,39,40,41]
Endocr Pract (2012) 18(4):4727
By combining them, Retatrutide aims to create a broader, more powerful effect than older medicines that focus on just one or two pathways