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A patient whose sleep is not restorative, who sleeps for seven or eight hours but wakes unrefreshed with elevated cortisol and poor morning energy, is typically a better Epithalon candidate

Both: Dose, route, and duration matter

This article explores in detail the science behind this hypothesis and its practical implications

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At its core dementia results from a combination of diminished synaptic connectivity among neurons and neuronal death in the entorhinal cortex, hippocampus and neocortex