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This is very important because cardiovascular disease continues to be the leading cause of death among people with Type 2 diabetes, and furthermore, Type 2 diabetes is a leading risk factor contributing to a recent rise in heart disease and stroke, said Amit Khera, M.D., M.Sc., FAHA, the volunteer chair of the American Heart Associations Advocacy Coordinating Committee and recipient of the Associations 2025 Chairmans Award

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In DIO mice, this daily dose of GLP-1GIPLani solidly outperformed semaglutide to further decrease body weight, food intake and fat mass, without difference in lean body mass, but with further improved glucose tolerance, greater decrease in blood glucose and similar reduction in plasma insulin (Extended Data Fig

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