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These studies suggest that GLP-1 and its receptor play a role in the pathophysiology of congenital hyperinsulinism and that targeting the GLP-1 receptor may be an effective treatment approach for this condition ( ATP hyperinsulinism and decreases glucose infusion rate requirements in infants with K ATP hyperinsulinism (35)

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FASEB J 7(11):10311038 Gaengel K et al (2009) Endothelial-mural cell signaling in vascular development and angiogenesis

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