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However, the convenience of a single morning dose means most researchers prefer once-daily administration, and the clinical data supporting split dosing specifically for AOD 9604 is limited

In early 2026, the FDA publicly announced its intent to take enforcement action against certain mass-marketed non-FDA-approved GLP-1 products

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This warning applies to all medications containing semaglutide, including Wegovy, as well as other GLP-1 agonists like Ozempic and Rybelsus, which are used for Type 2 diabetes (and off-label for weight loss)