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By preserving NAD+ and SAM in both fat and muscle tissue, NNMT inhibition may theoretically address the metabolic dysfunction underlying both excessive fat storage and impaired muscle maintenance

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An NNMT Inhibitor Increases Strength and Alleviates the Need for Muscle Recovery To test the effects of 5-amino-1MQ, the Texas-based research group divided aged mice into four groups: one sedentary group with low activity, another sedentary group given the compound, a group that underwent rigorous exercise without treatment, and another that underwent exercise and treatment

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