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These injections work best when combined with a healthy diet, regular exercise, and lifestyle changes

For example, transcriptomic analyses of hibernator-derived mammalian cells have identified glutathione peroxidase 4 (Gpx4) as a key mediator of cold resistance, highlighting the role of redox regulation in low-temperature survival (41)

A major shortcoming is their frequent failure to replicate human comorbidities (e.g., hypertension and diabetes), which profoundly alters copper homeostasis and cell death pathways

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