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The inactivation or silencing of Gpx4 gene expression can result in the death of the embryo, possibly due to developmental defects in the brain ( GPX4 are associated with sedaghatnia-type spondylometaphyseal chondrodysplasia, which causes bone, heart, and brain abnormalities and increased cell death (Smith et al., 2014)

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Blood and plasma glutathione measured in healthy subjects by HPLC: relation to sex, aging, biological variables, and life habits

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