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Furthermore, ROS interacts with cellular transduction pathways like protein kinase C/extracellular signal-regulated kinases (ERK)/mitogen-activated protein kinase (MAPK) pathway that can affect cell growth, cell proliferation, differentiation, apoptosis and gene expression [10, 11]

A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans

Hillerer KM, Slattery DA, Pletzer B

17 (1), e120

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