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cf-mtDNA is enriched in unmethylated CpG motifs that activate pattern-recognition receptors such as Toll-like receptor 9 (TLR9), triggering inflammatory and antiviral responses

Tolerance of high-dose (3,000 mg/day) coenzyme Q10 in ALS

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Clin Chem 53(5):940946 Franzini M, Corti A, Fornaciari I, Balderi M, Torracca F, Lorenzini E, Baggiani A, Pompella A, Emdin M, Paolicchi A (2009) Cultured human cells release soluble gamma-glutamyltransferase complexes corresponding to the plasma b-GGT

They have shown an increased potential in the development of safer and more efficient therapies, by offering solutions to several challenges associated with cancer therapy