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Medical-necessity and step-therapy denials are appealable with documentation

The challenge is that GLP-1 medications make you not want to eat so every meal needs to deliver high protein in a portion size your reduced appetite can handle

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These drugs can range from active pharmaceutical ingredients (APIs) composed purely of natural amino acids, as in the case of exenatide, to more complex molecules that incorporate noncanonical amino acids and are conjugated to small molecules (such as fatty acids), as in liraglutide, semaglutide, and tirzepatide resulting in a unique set of properties not observed with earlier peptide therapeutics

In the DCCTEDIC follow-up study, delayed gastric emptying was associated with other complications of diabetes, particularly severe retinopathy, and to a lesser extent with cardiovascular vagal dysfunction and severe nephropathy [28]