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Neurology 91(1):e62e66 Martinc B, Grabnar I, Vovk T (2015) Antioxidants as a preventive treatment for epileptic process: a review of the current status

Development 129 , 41714183 (2002)

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There is no evidence that either molecule needs to be cycled to prevent tachyphylaxis (a loss of efficacy usually due to the down regulation of receptors in the setting of high stimulation)