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This contrasts sharply with full-length human growth hormone, which can impair glucose tolerance and insulin sensitivity, potentially precipitating or worsening diabetes

Clinical trial registration EudraCT number 2015-005402-11

Managing side effects when on both therapies Side effect management is more nuanced when two therapies are running simultaneously

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FOXO4-DRI is a D-amino acid retro-inverso peptide that disrupts the intracellular interaction between FOXO4 and p53 in senescent cells, triggering p53-mediated apoptosis selectively in senescent rather than healthy proliferating cells