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About the study Researchers conducted a retrospective cohort study using de-identified electronic health records from the TriNetX United States Collaborative Network between January 2020 and November 2025

Thermal allodynia Mild temperature changes, warmth that would normally feel pleasant or cool air that would normally feel refreshing, instead produce pain

Patents will reshape the landscape: semaglutide loses composition-of-matter exclusivity in 2031, while tirzepatide extends to 2036, creating different windows for biosimilar entry

Intracellular retention is a common characteristic of childhood obesity-associated MC4R mutations

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