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Nicassio L, Fracasso F, Sirago G, Musicco C, Picca A, Marzetti E, Calvani R, Cantatore P, Gadaleta MN, Pesce V (2017) Dietary supplementation with acetyl-l-carnitine counteracts age-related alterations of mitochondrial biogenesis, dynamics and antioxidant defenses in brain of old rats

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NAPRT modulators Apart from the targets discussed above, one of the less explored yet crucial enzymes in NAD + biosynthesis is NAPRT, the rate-limiting enzyme of the PreissHandler pathway