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Surgical Treatments : In severe cases, procedures like flap surgery, tissue grafts, or bone grafts may be necessary to halt the diseases progression

Heck: This work was supported by the National Institutes of Mental Health R01MH112143 to DHH

Introduction Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) or Systemic Exertion Intolerance Disease (SEID) ( ME/CFS impacts all ages, races, and socioeconomic groups ( Due to the disabling symptoms which include cognitive and physical impairment worsened by exertion ( In this review paper, we will focus on describing ME/CFS in terms of symptoms, severity and burden, diagnostic criteria, causes and triggers