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[134] In March 2017, Lilly acquired CoLucid Pharmaceuticals for $960 million, obtaining the late clinical-stage migraine therapy candidate lasmiditan

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Besides, adenosine A1 receptor stimulation reduces D1 receptor-mediated GABAergic transmission from striato-nigral terminals and attenuates L-DOPA-induced dyskinesia in dopamine-denervated mice ( In addition, simultaneous blockade of both mGlu5 and A2AR in A2AmGlu5-D2R RM increases their efficacy in reversing parkinsonian deficits (32)

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