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Rapamycin, an inhibitor of mammalian target of rapamycin (mTOR) complex 1, exhibits cardioprotective effects in ferroptotic cells, where mTOR overexpression protects against iron-overload-induced cell death, a process exacerbated by mTOR deficiency (67, 68)
Instead, its activity is believed to be mediated via adipocyte-specific signaling cascades, which gives the fragment a uniquely narrow pharmacological footprint for a peptide of its molecular size and makes it attractive to investigators who want clean lipolytic readouts
Figure 6 The main function of K is to participate in plant metabolism, such as promoting photosynthesis and the transfer of photosynthesis products, regulating ion and water balance, promoting protein metabolism, and enhancing plant resistance (Mulet et al., 2023