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In mice, supplementation with auraptene (P45-60) and umbelliprennin in males (for 7 days between P51-60) [62] prevented POS-induced anxiety-like behavior in OFT and EPM at two months of age [63] and in the EPM immediately after treatment [62]

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The treatment can be combined with other therapies, including Botox and traditional fillers, to enhance overall skin appearance, making it a flexible, effective method for comprehensive skin renewal