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Developing selective Y2 receptor agonists can enhance PYYs anorexic and insulin-sensitizing effects while reducing actions on other Y receptors (such as Y1 receptor-mediated insulin secretion inhibition)

Plasmatic Klotho and FGF23 levels as biomarkers of CKD-associated cardiac disease in type 2 diabetic patients

These mice were intraperitoneally injected with either GLP-1 or saline (Figure 1A)