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5,21,22 Although causality is often difficult to establish, clinical case reports and postmarketing pharmacovigilance studies suggest a classwide signal that warrants continued monitoring

People working on maintaining weight loss after tirzepatide should keep nutrition high even as the weight stabilizes

Animal studies have demonstrated anti-inflammatory effects of GLP-1 receptor agonists in models where weight loss was minimal or absent, suggesting direct pharmacological actions on inflammatory pathways

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Acute Kidney Injury: Gastrointestinal side effects of compounded tirzepatide like diarrhea, nausea, and vomiting may cause a loss of fluids (dehydration), which may cause kidney problems if dehydration is severe