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Searching for GLP-1 on the North American Clinical Trials Registry yields approximately 2,600 clinical research records

Patients should be educated about symptoms of both hypothyroidism (fatigue, cold intolerance, weight gain, constipation) and hyperthyroidism (anxiety, palpitations, heat intolerance, tremor) to facilitate early detection of thyroid dysfunction

Attempts to normalize the tumor vasculature, such as with anti-VEGF therapies, have shown limited success, often due to the complex feedback loops involving hypoxia, metabolism, and angiogenic signaling (170)

J Cachexia Sarcopenia Muscle 1:921 Remels AH, Gosker HR, Langen RC, Schols AM (2012) The mechanisms of cachexia underlying muscle dysfunction in COPD