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Besides this, the combined therapy of l-carnitine and metformin further significantly decreased the time spent at the periphery of the open field as compared to the untreated diabetic rats and metformin-alone-treated diabetic rats

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Peptide Sequence : Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val The peptide has a molecular weight of 1,646.87 g/mol(molecular formula CHNO) and features two strategic amino acid substitutionsdesigned to enhance enzymatic stability and optimize receptor interaction: position 4 substitution of methionine with norleucine (Nle) and position 7 replacement of L-phenylalanine with D-phenylalanine (D-Phe)