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A systematic literature review and network meta-analysis comparing once-weekly semaglutide with other GLP-1 receptor agonists in patients with type 2 diabetes previously receiving 12 oral anti-diabetic drugs

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First month results in clinical trials showed an average weight loss of approximately 3.8 percent of baseline body weight at the 2.4 mg dose, but most researchers are still at 0.25 mg during this period

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Injection site reactions are a potential drawback, but many find the once-weekly schedule easier to manage