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For a patient friendly primer, see the patient friendly overview from the Cleveland Clinic explaining what nicotinamide adenine dinucleotide is and the essential role it plays in how every cell produces energy, and to understand what an in clinic protocol actually delivers, read our detailed guide to what an IV NAD+ protocol actually does inside your cells and the wellness benefits patients most commonly notice over a course of treatment

Most protocols call for 1-3 sessions spaced 4-6 weeks apart

LC-MS tells you which substance it is

Three RCTs met inclusion criteria The trials randomized 153 participants (74 participants to oral vitamin B12 and 79 participants to IM vitamin B 12 )