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Glucose metabolism effects are generally milder than with GH therapy, but individuals with diabetes or prediabetes should monitor blood glucose as GH can increase insulin resistance and blood sugar levels

They are claimed to treat or prevent conditions ranging from infant colic to cardiovascular disease, respiratory infections, and certain cancers

Administration (research setting): Typically studied via subcutaneous injection, often timed to support natural GH pulses (e.g., evening or fasting windows), depending on protocol design

Vero cells were detached from the flasks by treatment with trypsin (0.5 mg/ml)/EDTA (0.2 mg/ml) in PBS for 5 min at 37 C

Cardiovascular safety trial demonstrating that the DPP-4 inhibitor sitagliptin does not increase MACE or hospitalization for heart failure in patients with T2DM and high cardiovascular risk