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Casanueva FF, Moreno B, Rodriguez-Azeredo R, Massien C, Conthe P, Formiguera X, et al

When the spine or joints in the arms and legs do not move properly, the brain receives less accurate information about body position

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this was evidenced by the blunted organoid formation of crypt obtained from aged mice, which was rescued by restoring canonical Wnt signaling [125]

Trial data show that patients who continue therapy tend to maintain their loss, while those who stop tend to regain a substantial portion which is why it is framed as a maintenance therapy, not a temporary course