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"Beyond GLP-1: the next wave of weight-loss medication innovation." October 2025

Tirzepatide: dual GIP/GLP-1 receptor agonism Tirzepatide demonstrated that dual incretin receptor agonism could produce greater weight loss than earlier single-receptor approaches

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Pharma companies like Roche, Amgen, Pfizer, and AstraZeneca are among the contenders expected to release additional obesity drugs in the next three to four years

doi: 10.3390/jcm11061567 109