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Kidney function : Reports have indicated that semaglutide may cause kidney injury, especially in people who experience dehydration due to gastrointestinal side effects

The effects of GLP1RAs might also be caused by changes in other neurotransmitter systems, for example, GABA [27], as indicated by a preclinical study, where treatment with the GLP1RA semaglutide enhanced GABA release in the central nucleus of amygdala and infralimbic cortex neurons in alcoholnave rats

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Results may vary based on metabolism, routine, and adherence