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To make the hEC surface charge more positive the glycocalyx of hECs was digested with neuraminidase enzyme (1 U/ml, 1-h pretreatment) or cultures were treated with cationic lipid 1-(4-trimethylammoniumphenyl)-6-phenyl-1,3,5-hexatriene (TMA-DPH

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Full names of the substrates and enzymes are given in the Supplementary materials table of acronyms

Key Ingredients Water, Butylene Glycol, Caprylic/Capric Triglyceride, Glycerin, Cetyl Ethylhexanoate, Propanediol, Pentaerythrityl Tetraisostearate, Niacinamide, 1,2-Hexanediol, Polyglyceryl-10 Laurate, Vinyl Dimethicone, Hydrogenated Lecithin, Saccharide Hydrolysate, Ethylhexylglycerin, Adenosine, Niacinamide, Bakuchiol, 3-O-Ethyl Ascorbic Acid, Houttuynia Cordata Extract, Glutathione (5 ppm), Myosotis Sylvatica Flower/Leaf/Stem Extract, Oenothera Biennis (Evening Primrose) Flower Extract

Exogenous sources of antioxidants are needed to overcome stress conditions