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In particular, arachidonic acid (AA) and adrenic acid (AdA) are highly peroxidizable fatty acids that can be incorporated into membrane phospholipids and subsequently drive lipid peroxide propagation [35]
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However, excessive or dysregulated TLR9 activation has been implicated in sepsis-related organ injury ( Importantly, bacteria-induced mitochondrial dysfunction can trigger multiple forms of regulated cell death beyond apoptosis
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