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This is supported by the fact that several ME/CFS outbreaks have occurred in the same geographical region simultaneously (100) in the Faroe Islands during World War II upon the arrival of foreign army corps, and was eventually shown to be due to EBV (101)

The likelihood of pre-existing resistant clones is shaped by tumor size, baseline mutational burden, fitness costs, and microenvironmental constraints, making therapeutic failure an expected evolutionary outcome under strong selective pressure

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Subcellular proteomic mapping of lysine lactylation

They bind to specific receptors on target cells and trigger defined biological responses