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BPC-157's documented ability to modulate the nitric oxide pathway and reduce inflammatory cytokine expression in animal models suggests a potential role in the anti-inflammatory toolkit available to longevity-focused medicine, though this remains an extrapolation requiring human validation

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The data discussed here summarize some of the roles of endogenous estrogens, estrogen-based therapies, and estrogen-like molecules on brain homeostasis, particularly in neurogenesis, gliogenesis, and regulation of the neuroprotection/neurodegeneration balance

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(2012) analyzed ventricular CSF from PD and controls obtained in the immediate post-mortem period using a two-dimensional difference gel electrophoresis (2D-DIGE) coupled with mass spectrophotometry protein identification, and found differences between the 2 groups in 6 molecules: fibrinogen, transthyretin, apoE, clusterin, apoA1, and glutathione-S-transferase-Pi (GSTP)