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In cell studies, the complex stimulates fibroblasts to produce types I, III and IV collagen, elastin and glycosaminoglycans, while down-regulating matrix metalloproteinases that break down the skins scaffold.(pubmed.ncbi.nlm.nih.gov) These actions form the biochemical basis for its cosmetic before and after effects

doi: 10.1034/j.1399-3003.1999.14d02.x

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Compounding the problem is the fact that insurance companies are reluctant to cover these anti-obesity medications, since theyre considered by many to be vanity drugs, even though overwhelming evidence suggests obesity is linked directly to multiple comorbidities

These are not dangerous and typically fade within a few days