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Six glucagon-like peptide 1 (GLP-1) receptor agonists (GLP-1RAs) are approved for the treatment of type 2 diabetes, including 4 long-acting agents, but only 1 (liraglutide) is approved and 1 (semaglutide) under investigation for the treatment of obesity

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The ability of the antioxidant curcumin to rescue DF508-CFTR localization in cell lines (88) suggests that oxidants might be responsible for the cytoplasmic mislocalization of CFTR observed in alcoholic, idiopathic and autoimmune pancreatitis (81)