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FORMULATION GUIDELINES: Suggested concentration: UP to 1%-5% for face and neck preparations pH: 5.0-8.0 IMPORTANT POINT: Until now, reduced Glutathione was used to brighten skin by oral administration, but was ill-suited for topical application because it is unstable in aqueous form

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However, it is important to note that humans have fewer C-cells and GLP-1 receptors in the thyroid gland compared to rodents, and no C-cell changes have been observed in clinical trials involving patients treated with GLP-1 RAs [26]