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Similarly, exenatide-4 inhibits hepatocarcinogenesis independent of obesity and MASH resolution, acting through the cAMP-PKA-EGFR-STAT3 axis and mTOR modulation to suppress proliferation and reduce HCC multiplicity (Zhou et al., 2017)

Ouled-Haddou, H

The methylation pathway is particularly important in conditions where choline availability is low, as it allows for the synthesis of phosphatidylcholine from a readily available precursor, phosphatidylethanolamine

This GWAS approach resulted in one genome-wide significant signal with rs2880961 on chromosome 3 found to be the strongest genome-wide significant marker