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While sermorelin produces more modest GH elevations than direct HGH replacement, sustained therapy has been associated with meaningful body composition improvements

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doi: 10.3389/fnagi.2025.1665957 Received 14 July 2025 Accepted 25 September 2025 Published 10 October 2025 Volume 17 - 2025 Edited by Indrani Poddar, University of Minnesota Twin Cities, United States Reviewed by Shikha Grover, Dyne Therapeutics, United States Ayush Kumar Srivastava, SUNY Potsdam, United States Updates Copyright 2025 Invernizzi, Ciocca, Contaldi, Inverso, Calandrella, Mignone, Barichella, Isaias and Pezzoli

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