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Cold medication causes more tissue irritation because your subcutaneous tissue constricts in response to temperature change

Skin permeation studies Researchers have used isolated human skin and laboratory diffusion systems to study retention and penetration

(b) Mammalian cells In cultured V79 Chinese hamster cells, no induction of 8- azaguanine-resistant mutations after treatment with up to 1 mmol/litre dichlorvos (Wild, 1975), or of ouabain-resistant mutations after treatment with 1.25 - 5 mmol/litre dichlorvos, was found (Aquilina et al., 1984)

Cell 140 (6), 900917 (2010)

10.1016/j.omtm.2020.05.008 10 CollaboratorsG