Store unopened semaglutide in the refrigerator at 36F to 46F (2C to 8C), away from the freezer compartment and cooling elements
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However, a 2025 meta-analysis, which included more than 84,000 participants across 34 studies, found that people taking GLP-1s were 3.4 times more likely to experience hair loss compared with people not taking the drugs
These changes happen gradually, often over months, and many users do not notice them until the damage is significant
Symptoms may also become more noticeable after a dose increase because the body is adjusting to a stronger effect