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Our results suggest that CBS of the TSS pathway plays an important role in maintaining cysteine levels under restricted cystine availability or excess hemin exposure, and CBS upregulation by DMF increases the cellular glutathione levels to protect against ROS and ferroptosis stress in SCD

Take on an empty stomach, at least 10 minutes before meals

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To stain cell nuclei Hoechst 33342 dye (1 g/ml, 10 min) was used