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The results suggested that the combinations of GSTM1 (null) and GSTP1 (mutant), GSTM1 (null) and GSTT1 (null) can be risk factors for the development of wet AMD [99]

228,229,230 Inhibiting xCT The search for strategies and drugs aimed at inducing oxidative stress has revealed xCT to be a suitable targetincreased glutamate efflux through this antiporter is an important process for cells to generate sufficient glutathione to cope with high intracellular ROS levels

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Martinez-OutschoornUEBallietRMRivadeneiraDBChiavarinaBPavlidesSWangCet alOxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution

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