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Its an extremely new term, and it really gained popularity in the past few years as people using these medications were reporting less intrusive and repetitive mental noise around food, says Matthew Breit, PhD, RDN, a post-doctoral researcher and registered dietitian at the University of Colorado Anschutz School of Medicine who specializes in nutrition and lifestyle weight loss intervention

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A plausible explanation of this apparent dichotomy is that p53 promotes cell survival by preventing excessive increases in ROS under moderate oxidative stress, whereas when the oxygen species increase over a threshold level, it switches to becoming a ROS inducer, triggering cell death

Biochem Biophys Res Commun 161 : 113120