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Frozen grids were imaged using a Titan Krios microscope (Thermo Fisher Scientific) operated at 300 kV and equipped with an X-FEG electron source and a K3 direct electron detector (Gatan) with a Bioquantum post-column energy filter operated in zero-loss imaging mode with a 20 eV slit width

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Microphthalmia gene product as a signal transducer in cAMP-induced differentiation of melanocytes

These individuals appear to have a puzzling condition called GLP-1 resistance, where their bodies produce higher levels of the hormone targeted by these drugsbut dont respond to it properly