Variants in GLP1R (rs6923761) and GIPR (rs1800437) are associated with different metabolic responses and side effect profiles, information that may help contextualize treatment decisions post-cholecystectomy
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Incretins were identified afterward, and these are intestinal hormones released in response to nutrient ingestion, which then are going to potentially help with this glucose-induced insulin response
Chiasson, J.L., Acarbose for the prevention of diabetes, hypertension, and cardiovascular disease in subjects with impaired glucose tolerance: the Study to Prevent Non-Insulin-Dependent Diabetes Mellitus (STOP-NIDDM) Trial
Explosive Growth in Obesity Indications: Originally for diabetes, GLP-1 drugs are now predominantly being prescribed off-label and approved for weight loss