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The non-parametric KruskalWallis test and Duncans multiple range test was used to identify differences between each group

Among these preliminary studies, one found that, in cultured cells, Protandim activated Nrf2, a protein that stimulates genes that respond to free radicals and oxidative stress, and another found it to improve markers of oxidative stress in mice (Reuland, Free Radic Biol Med 2013

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While it can be inconvenient, it usually decreases as the body adjusts