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This rapid increase in prescription rates followed the recent approval of two GLP-1R agonists, semaglutide (Ozempic, Wegovy) and liraglutide (Victoza), for weight management in obese or overweight patients

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Although CD44 is expressed in normal cells, its alternative splicing isoforms, including CD44 variant 6 (CD44v6), are upregulated in tumor cells, contributing to tumor cell migration and metastasis by interacting with c-Met 111

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