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Sermorelin stimulation preserves negative feedback loops mediated by IGF-1, somatostatin, and other factors, creating a self-limiting system that helps prevent excessive GH production and associated risks like acromegaly-like symptoms, severe insulin resistance, or fluid retention

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Its intriguing aspect lies in its apparent capacity to expedite tissue repair and affect many biological processes associated with regeneration

Expression of insulin-like growth factor I stimulates normal somatic growth in growth hormone-deficient transgenic mice