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It activates both GIP and GLP-1 receptors, which are naturally occurring hormones involved in glucose homeostasis and appetite regulation

Read more: Wegovy dosage guide: Finding the right dose for weight loss results What do if youre not losing weight on Wegovy: A look at lifestyle factors Lifestyle intervention, calorie reduction, and exercise can play a big role in how much weight you lose with Wegovy: The medication reduces appetite, but what you do alongside it can influence how steady your progress is, how you feel day to day, and how well you maintain results

This summer, wanting to shed fat and gain muscle, he sought out retatrutide, a next-generation GLP-1, glucose-dependent insulinotropic polypeptide (GIP), and glucagon receptor agonista triple agonist targeting appetite, blood sugar, and metabolism