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Clinical Presentation Acute overdosage with hydrocodone bitartrate and acetaminophen tablets can be manifested by respiratory depression, somnolence progressing to stupor or coma, skeletal muscle flaccidity, cold and clammy skin, constricted pupils, and, in some cases, pulmonary edema, bradycardia, hypotension, hypoglycemia, partial or complete airway obstruction, atypical snoring, and death

Rare cases of NMS occurred during aripiprazole treatment in the worldwide clinical database

Once opened, the vial should remain refrigerated and used within the period indicated in the accompanying handling guidance

Patients across randomized trials achieved comparable weight loss and appetite reduction whether they received their weekly injection on Monday morning or Friday evening

This cost barrier is the single biggest reason they are not more widely used